Survival Analysis of Dengue Patients in Relation to Severity of Liver Dysfunction in Pakistan

The study aimed to analyze the survival of dengue patients in relation to liver dysfunction in Pakistan. This study was conducted by taking data from different Government as well as private tertiary care setups in Lahore from September 2010 to December 2010. A total of 60 patients were included in the study. All patients of either gender, admitted for treatment for dengue fever having age 15-69 years were taken. Patients were divided into 3 groups (Mild, moderate or severe liver dysfunction). The mean survival time for patients with mild, moderate and sever liver dysfunction was 66.000±5.477, 64.398±3.890 and 38.400±7.96 hours in hospital respectively with p-value < 0.01. A significantly higher survival rate for patients with mild and moderate liver dysfunction was found in this study as compared to severe type of liver dysfunction, i.e. (Log Rank Test)= 13.464 with p-value = 0.001. Conclusively, liver dysfunction is fatal for survival of dengue patients. It is therefore suggested to include identification of liver problem in differential diagnosis of dengue fever. This in future may help in better management of dengue patients and also to cope with this recent endemic in the country.